All products sold on this website are for Research Use Only (RUO). Not for human or veterinary use. Not approved by the FDA for any therapeutic purpose.All products sold on this website are for Research Use Only (RUO). Not for human or veterinary use. Not approved by the FDA for any therapeutic purpose.All products sold on this website are for Research Use Only (RUO). Not for human or veterinary use. Not approved by the FDA for any therapeutic purpose.All products sold on this website are for Research Use Only (RUO). Not for human or veterinary use. Not approved by the FDA for any therapeutic purpose.All products sold on this website are for Research Use Only (RUO). Not for human or veterinary use. Not approved by the FDA for any therapeutic purpose.
Research Overview: MOTS-C
Beauty / Anti-Aging / Antioxidant

Research Overview: MOTS-C

Mitochondrially derived peptide for metabolic research

Author: VCPeptides
Published: December 17, 2025
Read Time: 8 min read

Introduction

MOTS-C is a research compound used in laboratory investigations to study various biochemical and cellular processes. This article provides a comprehensive overview of the compound's mechanism of action, chemical properties, research applications, and handling guidelines for scientific research purposes. Researchers utilize MOTS-C in controlled laboratory settings to investigate cellular mechanisms, biochemical pathways, and experimental models. The compound falls within the Beauty / Anti-Aging / Antioxidant category and is employed in research settings to advance scientific understanding of biological processes.

Mechanism of Action

The mechanism of action of MOTS-C involves its interaction with specific cellular receptors and biochemical pathways. In laboratory research, MOTS-C has been studied for its effects on various cellular processes. MOTS-C is used in laboratory research to investigate metabolic regulation and mitochondrial function. Researchers investigate how MOTS-C modulates cellular signaling, receptor binding, and downstream biochemical cascades in experimental models. The compound's biological activity is typically evaluated through in vitro assays and ex vivo tissue studies, providing insights into its potential research applications. The stability of MOTS-C (shelf life: 36 months) is an important consideration for laboratory research. Proper storage and handling are essential to maintain the compound's biological activity and structural integrity throughout experimental procedures. Researchers typically assess the compound's stability under various conditions, including temperature, pH, and storage duration, to ensure reliable experimental results. The biological function of MOTS-C in research contexts involves its interaction with cellular targets, which may include receptors, enzymes, or other molecular components. Understanding these interactions helps researchers design experiments to investigate specific biological processes and pathways.

Chemical Background

MOTS-C has the chemical formula C77H120N20O26S with a molar mass of 1861.0 g/mol. The CAS registry number is N/A. The compound is also known by the following synonyms: Mitochondrial ORF of the Twelve S rRNA-c, MOTS-c, Humanin-related peptide. Additional chemical information can be found in PubChem (ID: N/A). The structural properties of MOTS-C contribute to its biological activity and research applications.

Laboratory Applications

MOTS-C is used in laboratory research to investigate various biochemical and cellular processes. MOTS-C is used in laboratory research to investigate metabolic regulation and mitochondrial function. Research applications include studies on insulin sensitivity, glucose homeostasis, metabolic syndrome, age-related metabolic disorders, and mitochondrial biogenesis in experimental models. The peptide has been investigated for its potential role in metabolic health and longevity pathways. Researchers typically employ MOTS-C in in vitro cell culture studies, ex vivo tissue experiments, and biochemical assays to understand its effects on cellular mechanisms and signaling pathways. The compound's lab-handling relevance is significant, as proper preparation, storage, and administration protocols are essential for obtaining reliable and reproducible research results. In vitro applications of MOTS-C involve studies conducted in controlled laboratory environments using cell cultures, tissue samples, or isolated biological systems. These studies allow researchers to investigate the compound's effects on specific cellular processes, receptor interactions, and biochemical pathways under controlled conditions. Ex vivo applications involve experiments conducted on tissues or organs removed from their natural biological environment but maintained in conditions that preserve their biological activity. These studies provide insights into how MOTS-C interacts with intact biological systems while maintaining experimental control. Researchers working with MOTS-C should follow established laboratory protocols, maintain sterile conditions during reconstitution and handling, and adhere to all safety guidelines. Proper documentation of experimental procedures, storage conditions, and handling protocols is essential for research reproducibility and scientific rigor.

Handling and Storage Guidelines

Storage Requirements: Store lyophilized powder at -20°C in a dry environment. Protect from light and moisture. Reconstituted solution should be stored at 4°C for up to 14 days. Maintain sterile conditions during reconstitution. Handling Guidelines: Handle using sterile techniques and appropriate laboratory personal protective equipment (PPE). Use in well-ventilated areas. Avoid inhalation, ingestion, or skin contact. Follow standard laboratory safety protocols. Refer to Material Safety Data Sheet (MSDS) for complete safety information.

Cross-Linked Research

Related research peptides in the same category:

External Citations

Reference authoritative research sources:

Research Use Only Disclaimer

All materials are sold strictly for laboratory research use only. Not for human administration. MOTS-C is not approved by the FDA for any therapeutic purpose. All research should be conducted in accordance with applicable laws and regulations.

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Research Reference Disclaimer

The information in this article is for research and reference purposes only. It does not constitute medical advice or recommendations for human or veterinary use.

The information presented in this article is for general research reference only and is not medical, legal, or nutritional advice. All content is intended for educational purposes in the context of laboratory research. Nothing in this article should be construed as prescribing, diagnosing, or treating any medical condition.

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